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Peroxynitrite Inactivation of Tyrosine Hydroxylase: Mediation by Sulfhydryl Oxidation, not Tyrosine Nitration

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Tyrosine hydroxylase (TH) is the initial and rate-limiting enzyme in the biosynthesis of dopamine (DA). TH activity is significantly diminished in Parkinson

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Peroxynitrite Inactivation of Tyrosine Hydroxylase: Mediation by

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Modification of sulfhydryl groups in TH by ONOO − and thiol

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